Domperidone+Pantoprazole

Molecule Description

Domperidone+Pantoprazole is a combination medicine. It is used for the treatmen

t of gastrointestinal reflux disease (GERD) which does not respond to pantoprazole alone. It provides relief from symptoms of acid reflux disease like heartburn and chest discomfort. Both the medicines, together work by reducing the amount of acid produced in the stomach and improves the motility in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Domperidone+Pantoprazole is available in the form of tablet, capsule. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting domperidone+pantoprazole.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Domperidone+Pantoprazole

Domperidone+Pantoprazole is used to treat gastrointestinal reflux disease (GERD), not responding to pantoprazole alone.

Contraindications of Domperidone+Pantoprazole

When should one not use Domperidone+Pantoprazole

If you are allergic to pantoprazole+domperidone or similar medicines
If you are pregnant, planning to get pregnant or are breastfeeding.
If you are taking any medications containing rilpivirine
If you are suffering from bleeding in the digestive system.
If you have any tumour of the pituitary gland (prolactin pituitary tumours)
If you have problems with your heart, liver or kidney.

Side effects of Domperidone+Pantoprazole

Common side effects of this drug are:

Dry mouth
Weakness
Diarrhoea
Headache
Skin rashes
Altered taste

Precautions and Warnings of Domperidone+Pantoprazole

Pregnancy

Can I take domperidone+pantoprazole during pregnancy?

It is not advised to take pantoprazole+domperidone during pregnancy until it is considered essential by the doctor and potential risks justify the benefits.

Breast Feeding

Can I take domperidone+pantoprazole while breastfeeding?

Pantoprazole+Domperidone passes in the breastmilk in a small amount. Your doctor may prescribe you this medicine while you are breastfeeding, only if it is necessary. Inform your doctor if you are a nursing mother.

Driving

Can I drive if I have consumed domperidone+pantoprazole?

Pantoprazole+Domperidone may cause dizziness, thus you need to be cautious while driving.

Alcohol

Can I consume alcohol with domperidone+pantoprazole?

Avoid consuming alcohol with pantoprazole+domperidone, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if

You have problems with your liver or kidney.
You are suffering from any heart like heart failure, heart rhythm problems, electrolyte imbalance
You have a stomach tumour/cancer
You develop watery/black stools or fever after taking this medicine.
You have low levels of vitamin B12
You have a history of fractures or have osteoporosis or are taking steroids.
You are taking medicines to treat HIV.
You get rashes on your skin on exposure to sun after taking this medicine.
Your blood magnesium levels may drop, if you are taking this medicine for more than three months. Your doctor may perform regular tests.
Taking pantoprazole+domperidone for more than one year may increase the chances of developing bone fractures.

Mode of Action of Domperidone+Pantoprazole

How Does It Work?

A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Pantoprazole binds to this proton pump in stomach cells, thus blocking acid secretion.
Domperidone increases the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Interactions of Domperidone+Pantoprazole

Interactions with other medicines

Some medicines can affect the way domperidone+pantoprazole works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking medicine to treat your heart problems, mental health problems, fungal or bacterial infections or are taking blood thinners.
Rilpivirine or methotrexate should not be used along with this medicine.

Dosage of Domperidone+Pantoprazole

Overdose

Overdose symptoms may lead to uncontrolled muscle movements, aggression, fits, sleepiness, slurred speech, anxiety etc.

Missed a Dose

If you have missed any dose of pantoprazole+domperidone then take it as soon as you remember. If it is already time for the next dose then skip the missed dose and follow the regular dosing schedule. ...

Content Details

WRITTEN BY

Dr. Mansi Savla

B. Pharm, PharmD

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: In which all dosage forms is domperidone+pantoprazole available?

A: Domperidone+Pantoprazole is available in the form of tablet, capsule

Q: What is gastro-intestinal reflux disorder (GERD)?

A: There is a valve-like structure in between stomach and food pipe, which allows food to pass from food pipe into the stomach. In Gastro-intestinal reflux disorder (GERD), the acid from the stomach, goes back, upwards in the food pipe. This acid then causes chest discomfort, pain, burping and damage to the food pipe.

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Last Updated on: 07 Dec 2021 | 12:15 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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